Microbial 'omics

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single-profile-db [artifact]

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A DB-type anvi’o artifact. This artifact is typically generated, used, and/or exported by anvi’o (and not provided by the user)..

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Provided by


Required or used by

anvi-import-taxonomy-for-layers anvi-interactive anvi-merge


An anvi’o database that contains the same information as a merged profile-db, namely key information about the mapping of short reads in a single sample to your contigs.

You can think of this as a extension of a contigs-db that contains information about how your contigs align with a single one of your individual samples. If you have more than one sample, you’ll probably want to use anvi-merge to merge your databases into a merged profile-db. The vast majority of programs that use a profile database will also ask for the contigs database associated with it.

A single profile database contains information about how the short reads in a single BAM-file (see bam-file) map to the contigs in a contigs-db. Specificially, a profile database contains

  • the coverage and abundance per nucleotide position for each contig
  • variants of various kinds (single-nucleotide, single-codon, and single-amino acid)
  • structural variants (ex insertions and deletions)

Once created, a single profile database is almost interchangable with a profile-db (even though the names can be a little confusing. Think of a single-profile-db as a type of profile-db, since it has only a few differences). The main differences between the two are as follows:

If you want to look at the contents of a single profile database, you can do so using anvi-interactive.

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