Microbial 'omics

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internal-genomes [artifact]

Table of Contents


A TXT-type anvi’o artifact. This artifact is typically provided by the user for anvi’o to import into its databases, process, and/or use.

Back to the main page of anvi’o programs and artifacts.

Provided by


Required or used by

anvi-compute-functional-enrichment anvi-compute-genome-similarity anvi-dereplicate-genomes anvi-display-functions anvi-estimate-metabolism anvi-gen-genomes-storage anvi-get-sequences-for-hmm-hits anvi-meta-pan-genome anvi-script-gen-functions-per-group-stats-output anvi-script-gen-hmm-hits-matrix-across-genomes


An internal genome is any bin described in an anvi’o collection stored in an anvi’o profile-db. You can obtain one of these by binning a metagenome assembly (stored in an anvi’o contigs-db), which you can do either manually in the interactive interface or automatically with a binning software, and saving or importing it into a collection.

The internal genomes file format enables anvi’o to work with one or more bins from one or more collections that may be defined in different anvi’o profile-db files. A TAB-delimited internal genomes file will be composed of at least the following five columns:

name bin_id collection_id profile_db_path contigs_db_path
Name_01 Bin_id_01 Collection_A /path/to/profile.db /path/to/contigs.db
Name_02 Bin_id_02 Collection_A /path/to/profile.db /path/to/contigs.db
Name_03 Bin_id_03 Collection_B /path/to/another_profile.db /path/to/another/contigs.db
(…) (…) (…) (…) (…)

Please make sure names in the name column does not include any special characters (underscore is fine). It is also a good idea to keep these names short and descriptive as they will appear in various figures in downstream analyses.

Additional columns

In some cases additional columns may be required to be in this file. Below is a table of the possible columns you may need.

header description required for
group name of the group that the genome belongs to (can be empty) anvi-compute-functional-enrichment

Also see external-genomes and metagenomes.

Edit this file to update this information.